By Ernie Mundell and Robert Preidt
HealthDay Reporter

THURSDAY, March 11, 2021 (HealthDay Information) — The trauma and lack of stroke can usually depart survivors with long-term depression, and girls seem like at particular threat, new analysis exhibits.

“We didn’t count on that the cumulative threat of depression would stay so persistently elevated,” mentioned examine creator Dr. Laura Stein, an assistant professor of neurology on the Icahn Faculty of Drugs, Mount Sinai, in New York Metropolis.

She mentioned that, all too usually, “post-stroke melancholy just isn’t merely a transient consequence of difficulties adjusting to life after stroke.”

Within the examine, Stein’s staff analyzed knowledge from Medicare sufferers aged 65 and older who have been hospitalized for both ischemic stroke (greater than 174,000) or heart attack (greater than 193,000) from July 2016 to Dec. 31, 2017. An ischemic stroke is the most typical type of stroke and is brought on by blocked blood stream to the mind.

The sufferers have been adopted for a median of 1.5 years. These with any historical past of melancholy inside the six months earlier than their stroke or coronary heart assault have been excluded.


Whereas melancholy can have an effect on any coronary heart affected person, Stein’s group discovered the danger for melancholy was about 50% greater amongst stroke survivors than amongst coronary heart assault survivors.

Anxiousness usually performed a job: A historical past of anxiety was present in 10.3% of stroke sufferers and 11.8% of coronary heart assault sufferers, and stroke sufferers with a historical past of hysteria have been practically twice as prone to develop melancholy as these with out anxiousness, the examine confirmed.

Gender and youthful age additionally appeared to matter: Sufferers 75 and older have been 19% much less prone to be recognized with melancholy in comparison with youthful sufferers, and girls who’d survived a stroke have been 20% extra prone to develop melancholy in comparison with male survivors.

The findings are from two preliminary research to be introduced later this month on the digital American Stroke Affiliation’s annual assembly.

“Despair following stroke is sort of 3 times as frequent as it’s within the common inhabitants and should have an effect on as much as a 3rd of stroke sufferers,” Stein mentioned in an affiliation information launch. She’s additionally an attending neurologist at Mount Sinai and Mount Sinai Queens Stroke Facilities in New York Metropolis.


One specialist unconnected to the brand new examine mentioned the findings echo the expertise of many sufferers.

Brittany LeMonda is senior neuropsychologist at Lenox Hill Hospital in New York Metropolis. She mentioned the explanation why stroke is extra apt to result in melancholy than coronary heart assault is obvious: “People who are suffering stroke may additionally expertise higher incapacity — and lack of autonomy — whereas coronary heart assault sufferers don’t usually endure the identical diploma of life modifications.”

Recognizing these sufferers at highest threat for post-stroke melancholy could also be essential “for speedy intervention and higher outcomes,” she added.

Stein agreed. “Our present findings spotlight the necessity for energetic screening and remedy for melancholy within the time interval instantly and nicely after the stroke, and the significance of screening all stroke sufferers for post-stroke melancholy, together with girls and people with a historical past of psychological sickness,” she mentioned.

Dr. Andrew Rogove directs stroke providers at South Shore College Hospital in Bay Shore, N.Y. He supplied up one caveat to the examine, noting that “the inhabitants studied was over 65 years outdated. It could be fascinating to see the charges of post-stroke melancholy in a youthful inhabitants and to evaluate whether or not there are gender variations within the frequency of post-stroke melancholy on this inhabitants.”


As a result of the findings are to be introduced at a medical assembly, they need to be seen as preliminary till revealed in a peer-reviewed journal.

Extra info

The Coronary heart and Stroke Basis has extra on depression after stroke.

SOURCES: Brittany LeMonda, PhD, senior neuropsychologist, Lenox Hill Hospital, New York Metropolis; Andrew Rogove, MD, PhD, medical director, Stroke Companies, South Shore College Hospital, Bay Shore, N.Y.; American Stroke Affiliation, information launch, March 11, 2021


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